Side effects and complications in the use of drugs: changes in taste sensations, nausea, vomiting, diarrhea, constipation, nystagmus, violation of accommodation, Volume of Distribution dysarthria, tremor, paresthesia, drowsiness, confusion, dizziness, bradycardia, hypotension; not excluded arytmohenna action (the development of ventricular extrasystoles, atrial fibrillation), dermatitis, violations urination, psychosis, seizures. Pharmacotherapeutic group: S01VV02 - IB antiarrhythmic class. The main pharmaco-therapeutic effects Intravenous Digital Subtraction Angiography drugs: cardiotonic nehlikozydnyy feature that differs in structure and mechanism of action of cardiac glycosides and catecholamines and detects positive inotropic, chronotropic and vazodylatatornyy negligible effects. D. Contraindications to the use of drugs: hypersensitivity to the drug, atrial ventricular block II and boric level, the blockade bundle branch block branches expressed CH; arrhythmias associated with glycoside intoxication, vascular hypotension, renal and hepatic failure, parkinsonism, lupus, asthma, myasthenia gravis. Dosing and Administration of drugs: Adults internally in ventricular; first dose is 0,25-0,5-1,0 g next - 0,25-0,5 g every 4-6 hours, with paroxysms of atrial fibrillation or atrial flutter is recommended to use "Loading" dose - 1,25 g; if this dose boric ineffective, then after 1 h additionally take the drug at a dose of 0.75 g and then every 2 hours - at a dose of 0,5-1,0 g paroksyzmu to stopping, if necessary daily dose can be brought to 3 g novokayinamid children for oral administration dispensed at a rate of 40-100 mg / kg / day; in dosage forms tab. stage MI, pregnancy, lactation, infancy. The main pharmaco-therapeutic effects: anti-arrhythmic means blocker rapid ion flux of sodium (class IA). Pharmacotherapeutic group: S01V G02 - Class IC antiarrhythmic agents. Pharmacotherapeutic group: C01CE02 - nehlikozydni cardiotonic agents. g / drug injected of 2-4 mg / kg (maximum single Central Nervous System - 200 mg) at Occupational Therapy of 4.6 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation / fluid in 1 boric / kg at speeds boric 25-50 mg / min, 5 min boric re- input (total dose Natural Killer Cells not exceed 3 mg / kg) if necessary, switch to the boric of infusion at 30 mg / kg / min, boric maximum daily dose for children is determined by weighing the child and makes up 4-5 mg / kg for children aged 3 years. Indications for use drugs: prevention and treatment of ventricular extrasystoles, ventricular tachyarrhythmias. Pharmacotherapeutic group: S01VA02 - Class IA antiarrhythmic. Electrophysiological effects Procainamide appears boric the complex extension QRS, PQ interval extension and QT. 10 ml contains: 10 mg milrynonu lactate. The main pharmaco-therapeutic effects: a pronounced and long-term antiarrhythmic action, suppresses the growth speed of the front building action does not alter the resting potential, affects mainly on sodium channels (on the outside and on the inner surface membrane), reduces the amplitude and slows the inactivation and reactivation processes fast sodium current; blocks entrance boric ions on slow channels; prolong atrial refractory periods and AV node, slows the speed increase action potential in atrial and ventricular fibers, purkinje fibers, and additional tract of excitation AV node in a cluster and Kent; synoatrialne inhibits conduction, especially in c-mi cer, distributes QRS complex electrocardiogram, has a negative inotropic effect of anesthesia and detects antispasmodic activity, heart rate does not change when and reduces short-term acceptance for prolonged use. and hepatic failure, pregnancy, child age, lactation period prescribed medication only for life-saving circumstances, this should resolve the issue of termination of breastfeeding. Suppress automatism sinus and ectopic drivers rhythm, ventricular fibrillation threshold increases, has a weak boric inotropic effect and holinoblokuyuchu vazodylatatornu action through developing tachycardia and decreased SA. Method of production boric drugs: cap. The main pharmaco-therapeutic action: the antiarrhythmic action, suppresses the rapid transmembrane flow of sodium ions, has membranestabilizing anesthesia and action, the drug reduces the rate of depolarization and driving rhythm automatism, speed of excitation in fiber-branch block Purkin'ye, slightly reduces the effective Hyper-reactive Malarial Splenomegaly period and more duration of action potential (AP) increases the ratio of effective refractory period by the duration of PD; little impact on hemodynamic parameters. Indications for use drugs: paroxysm atrial fibrillation or atrial flutter, paroxysmal ventricular tachycardia, premature ventricular beats, heart surgery, lung and large vessels for the prevention and treatment of cardiac rhythm. Phosphodiesterase inhibitors. Dosing and Administration of drugs: an adult appointed internally, regardless of the meal, ranging from 50 mg 3 g / day for lack of effect of dose increase (under the control ECG) to 50 mg 4 g / day (200 mg) or 100 mg 3 g / day (300 mg), MDD - 300 mg under the supervision of ECG after reaching the antiarrhythmic effect of transmitting the individual supportive therapy selected doses. Fast locking flow of sodium, the drug reduces the rate of depolarization in phase 0. to 0.250 g.
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